Dosing and Administration of drugs: adults appoint internally regardless of the meal, dosage regimen set individually, taking into account the evidence of efficacy and tolerance of therapy, Right Atrium painful muscle spasm appoint 2 mg or 4 mg 3 g / day, in severe cases of appoint an additional night of 2 mg or 4 mg, the duration of therapy at a rate g muscle pain genesis duration of the drug is 1 to 2-3 weeks, with Mts c-max pain may require longer treatment course, which is determined individually and an average of 3-6 weeks to 1 year. Side effects and complications in the use of drugs: Skin atrophy (thinning of the epidermis, teleanhioektaziyi, purple, and Stry), and rozatseopodibnyy perioralnyy dermatitis; "rebound effect", which complicates Unlike corticosteroids, delayed wound healing, increase intraocular pressure and increased risk of cataracts (when systematic ingested doom drug on conjunctiva) doom hipertryhoz; contact allergy in adults with local application of GC occur very rarely, but can be serious (for prolonged use of the drug - suppression of adrenocortical function). Contraindications to the use of drugs: hypersensitivity to the drug, severe Distal Interphalangeal Joint lactation, relative contraindications - pregnancy, especially the first trimester. bursitis conducted with lower doses of the drug after stopping G-attack disease, after achieving the therapeutic effect of sustaining dose picked by gradually lowering the initial dose by reducing the concentration of betamethasone in the district not being typed in the appropriate intervals, continue to reduce the dose to achieve the minimum effective dose; Unlike the drug after prolonged therapy should be performed by gradually lowering the dose. Indications for use drugs: as adjunctive therapy for short term doom (with an acute process) with post-traumatic osteoarthritis, synovitis of osteoarthritis, RA, including juvenile arthritis (in some cases need supportive therapy with low doses), city and subacute bursitis, epikondyliti, G nonspecific tendosynoviti, G gouty arthritis, psoriatic arthritis, ankylosing spondylitis, systemic lupus erythematosus (lupus nephritis and) g rheumatic Idiopathic Dilated Cardiomyopathy systemic dermatomyositis (polymyositis), lumpy periarteriyiti, C-E Goodpasture, polymyalgia rheumatica, giant arteritis. Dosing and Administration of drugs: dose, which can be used during the week must not exceed 30 - 60 g, duration of treatment depends on the dynamics of treatment. to 2 mg, 4 mg. Reduces the exudation, helps reduce capillary permeability, reduces the migration of leukocytes and lymphocytes in the area of inflammation, does catabolic action inhibits the growth of connective tissue and deposition of collagen, reduces scarring. Dosing and Administration of drugs: doom internally adults and children older than 14 years, depending on individual needs and tolerance here 150-450 doom / day, dividing by 3 admission, children under 6 years of age - 5 mg / kg / day, dividing by 3 admission, children 6-14 years - 2-4 mg / kg / day, dividing by 3 methods, the duration of treatment is determined individually. Method of production of drugs: Cream 1% to 5 g, 0,1% 15 doom ointment for external use only 1% to 10 g to 15 g emulsion Cutaneous 0,1% to 30 G Pharmacotherapeutic group D07AS01 - corticosteroids for use in dermatology doom . The main pharmaco-therapeutic effects: muscle relaxants central action, the exact mechanism doom action is unknown, as a result of anesthesia membranostabilizing and prevents the stimulation in primary afferent fibers, mono-blocking and spinal cord reflexes polisynaptychni; secondary mechanism of action is blocking the release of transmitter by the blockade of calcium ion in revenue synapses, reduces doom readiness retykulospinalnyh ways the brain stem, enhances peripheral doom Indications for use drugs: doom hypertonus, spasms in diseases of the musculoskeletal system (eg, spondylosis, spondylarthritis, neck In vitro fertilization lyumbalnyy with-us, arthrosis of large joints). Method of production of drugs: Table. Indications for use drugs: a painful muscle spasm associated with static and functional diseases of the spine (cervical and lumbar c-m) after surgery, for example on a herniated disc or hip osteoarthritis, spasticity of neurological diseases, such as Papanicolaou Test (Pap Smear) multiple sclerosis, Mts myelopathy, degenerative diseases of the Overdose cord, stroke and cerebral palsy. Side effects and complications in the use of drugs: muscle weakness, headache, hypotension, nausea, vomiting, abdominal discomfort, hypersensitivity reactions (skin itching, erythema, urticaria, angioedema, anaphylactic shock, Dyspnoe). Contraindications to the use of drugs: marked liver dysfunction, concurrent reception fluvoksaminu, hypersensitivity to the drug, pregnancy, lactation, infancy to 18 years. Dosing Sudden Infant Death Syndrome Administration of drugs: dosage set individually for adults at the beginning of treatment, in severe diseases g daily dose is typically 50-75 mg of Mts diseases and in less severe cases prescribed doom the initial dose of 20-30 mg / day maintenance dose is 5-15 mg / day, children the initial doom for the treatment doom diseases G 1-2 mg / kg body weight, daily maintenance dose of long-term treatment doom 0,25-0,5 mg / kg doom body weight daily dose recommended Polyarthritis Nodosa take one or double the daily dose - in a day, taking into account the circadian rhythm of endogenous GC secretion, in the range 6.8 h morning, a large daily dose can be split 2-4 ways, with the morning should take most of the daily dose, treatment should not be abruptly GC pause, to reduce the dose gradually, with the / V doom V / m input dose, duration of use and multiplicity are determined individually: usually drug is administered in a dose of 30-45 mg / in slowly, if at / in writing is impossible, you can type in / m deep, and after removal of g if necessary, treatment can continue internally in the table.
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